Glycine, USP36, Food Grade |56-40-6|
CAS No:56-40-6
Molecular formula:C2H5NO2
Mol. mass: 75.07 g·mol−1
Certificate Of Analysis: USP36/FCC FOOD GRADE
Introduction:
Glycine (abbreviated as Gly or G) is an organic compound with the formula NH2CH2COOH. Having a hydrogen substituent as its side-chain, glycine is the smallest of the 20 amino acids commonly found in proteins.
Glycine is a colourless, sweet-tasting crystalline solid. It is unique among the proteinogenic amino acids in that it is not chiral. It can fit into hydrophilic or hydrophobic environments, due to its minimal side chain of only one hydrogen atom.
Physiological function:
The principal function of glycine is as a precursor to proteins, such as its periodically repeated role in the formation of Collagen helix in conjunction with Hydroxyproline. It is also a building block to numerous natural products.
1.As a biosynthetic intermediate
In higher eukaryotes, D-Aminolevulinic acid, the key precursor to porphyrins, is biosynthesized from glycine and succinyl-CoA. Glycine provides the central C2N subunit of all purines.
2.As a neurotransmitter
Glycine is an inhibitory neurotransmitter in the central nervous system, especially in the spinal cord, brainstem, and retina. Glycine is a required co-agonist along with glutamate for NMDA receptors. In contrast to the inhibitory role of glycine in the spinal cord, this behaviour is facilitated at the (NMDA) glutaminergic receptors which are excitatory.
There is some evidence showing that 3000 milligrams of glycine before bedtime improves sleep quality.Glycine has also been positively tested as an add-on treatment for schizophrenia.
Uses:
1. Animal and human foods
Other markets for USP grade glycine include its use an additive in pet food and animal feed. For humans, glycine is sold as a sweetener/taste enhancer. Certain food supplements and protein drinks contain glycine. Certain drug formulations include glycine to improve gastric absorption of the drug.
2. Cosmetics and miscellaneous applications
Glycine serves as a buffering agent in antacids, analgesics, antiperspirants, cosmetics, and toiletries. Many miscellaneous products use glycine or its derivatives, such as the production of rubber sponge products, fertilizers, metal complexants.
3. Chemical feedstock
Glycine is an intermediate in the synthesis of a variety of chemical products. It is used in the manufacture of the herbicide glyphosate. Glyphosate is a non-selective systemic herbicide used to kill weeds, especially perennials and broadcast or used in the cut-stump treatment as a forestry herbicide.
4. Research and Development
Glycine is a significant component of some solutions used in the SDS-PAGE method of protein analysis. It serves as a buffering agent, maintaining pH and preventing sample damage during electrophoresis. Glycine is also used to remove protein-labelling antibodies from Western Blot membranes to enable the probing of numerous proteins of interest from SDS-PAGE gel.
Production Capacity: 10,000 mts/year
Brief Introduction to our mill: Our Company Concentrates On The Developing,Processing and Selling of The Amino Acid. The Main Products Include Glycine,Lysine,Alanine,Methionine,Threonine,Disodium Succinate, Etc. Also We Agent for Vitamins And Sweeteners. It Mainly Covers Series Of Amino Acid,Pharmaceutical Intermediates,BPC, Etc. We Have Established The Scientific Standard
Specification:
Product Name: | Glycine | Reference standard: | USP28 |
Quantity: | 1000kgs | BatchNo:140408001 | Package:25kg/bag |
Manu date: | 2014.04.08 | Sampling date: | 2014.04.08 |
Send out date: | April 10, 2014 | Expiry date: | 2016.04.07 |
Item | Specifications | Results | |
Appearance | White crystalline powder | White crystalline powder | |
Assay (C2H5NO2),% | 98.5~101.5 | 99.0 | |
Loss on drying,% max | 0.2 | 0.15 | |
Residue on ignition,% max | 0.1 | 0.04 | |
Chloride (as Cl),%max | 0.007 | <0.007 | |
Sulphate(as SO4),%max | 0.006 | <0.006 | |
Heavy metals (as Pb),% max | 0.001 | <0.001 | |
PH value(5%in water) | 5.5~6.6 | 6.0 | |
Arsenic(as As),%max | 0.0001 | <0.001 | |
Ammonium(as NH4 ),%max | 0.02 | <0.02 | |
Oraganic volatile impurities | Complies | Complies | |
Hydrolyzable Substances | Complies | Complies | |
Iron (as Fe) , %max | 0.001 | <0.001 | |
Conclusion: This product conforms to requirements of USP28 grade standard. |
It's a Non-Dangerous Goods.
Packing: in 25kgs kraft bag onpallets, 20mts in 1x20'fcl;
in 25kgs kraft bag without pallets, 22mts in 1x20'fcl.